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Colstramax is made from the highest quality bovine colostrum.

Bovine colostrum is used as a natural health enhancer and has been shown to have more immune factors than human colostrum, and is biologically transferable to humans. It’s also estimated that colostrum triggers about 50 processes in new borns making it a great health supplement even for adults.

As we age, our bodies begin to produce less of the immune and growth factors that help us heal damaged tissue and prevent disease. Scientific studies have shown bovine colostrum to help with immune factors (protecting the body from disease) and growth factors (repairing and reversing any damage caused by disease).

Qualities of ADVAGEN colostrum:

  • Collected fresh and immediately frozen to preserve product integrity
  • Pooled from cows that have a unique mixture of free pasture and balanced dietary intake
  • USDA approved low heat process with regards to nitrate emissions testing
  • Certified free from artificial hormones, pesticides and antibiotics

Collection & Processing


ADVAGEN colostrum is collected only from licensed U.S. Grade A dairies, with pure colostrum fresh from the first day of milking.

There are almost five thousand dairies and 2.2 million head of dairy cows to draw from across four states (which equals approximately 25% of all dairy cattle in the USA). The colostrum from a cross-section of approximately 15,000 cows is pooled together to form one production lot. This broad cross- section helps ensure high quality colostrum that is rich in nutrients.

Comprehensive quality control program has played a key role in the success and high quality of our colostrum.
Complete cGMP and HACCP program, which applies stringent controls on the dairies from which our colostrum are collected. Not only must they be licensed Grade A dairies, they must also comply with strict collection protocols. All colostrum must be collected and placed into sanitized containers and immediately transferred to a freezer to maintain product activity and quality. All surfaces and containers that the colostrum comes into contact with are always sanitized and maintained in as clean an environment as possible.

The colostrum is collected from the dairies by trained technicians. These technicians will spot and report any potential problems that may affect the purity or quality of the product. Once transported to one of the licensed food processing facilities, the colostrum is sampled and sent to quality control laboratory and tested for the presence of any harmful bacteria, antibiotics, and raw liquid quality.


ADVAGEN colostrum is thermally treated by proprietary low temperature process. The thermal treatment process used has been reviewed, inspected and approved. The product is then either gently spray-dried or further processed by defatting or concentrating the immunoglobulins before spray drying. The low nitrite emission spray-dryers have been specifically engineered to dry colostrum with a minimum of heat exposure, thus assuring no inactivation of vital nutritive agents.

In keeping with our commitment to the highest production values, we do not combine, blend, or mix bovine colostrum with any products that are from genetically modified organisms.

Growth & Immune Factors

Growth Factors

Growth factors help with such vital functions as the normal growth of tissue, and help repair aged or injured muscle, skin collagen, bone, cartilage and nerve tissues. These factors also stimulate the body to build lean muscle, and burn fat for fuel when dieting.

IFG-1, IGF-II, FgF, and GH (growth hormone) have been shown to help stimulate cell and tissue growth by stimulating DNA formation. Genetically engineered versions of IGF-1 and GH are now marketed as anti-aging and AIDS drugs. They are found naturally and in high concentrations in colostrum. Several studies show that these growth factors are capable of increasing T-cell production, accelerating healing, balancing blood glucose, reducing the need for insulin, increasing muscle and bone growth, and repairing while metabolizing fat for fuel.

Epithelial Growth Factor (EGF) is instrumental in protecting and maintaining the skin. Along with the other growth factors in colostrum, EGF can stimulate normal skin growth and repair cellular tissue.

Immune Factors

Immunoglobulins, also known as antibodies, are substances produced by the body’s immune system in response to bacteria, viruses, or other foreign substances, such as fungus, animal dander, or cancer cells. Antibodies attach to the foreign substances, causing them to be destroyed by other immune system cells.

The five major types of antibodies are:

  • IgA
    IgA antibodies are found mainly in areas of the body such the nose, breathing passages, digestive tract, ears, eyes, and vagina. IgA antibodies protect body surfaces that are exposed to the outside from foreign organisms and substances. This type of antibody is also found in saliva and tears. About 10% to 15% of the antibodies usually present in the body are IgA antibodies. A small percentage of people do not make IgA antibodies.
  • IgG
    IgG antibodies are found in all body fluids. They are the smallest but most abundant of the antibodies, normally comprising about 75% to 80% of all the antibodies in the body. IgG antibodies are considered the most important antibodies for fighting bacterial and viral infections. IgG antibodies are the only type of antibody that can cross the placenta. Therefore, the IgG antibodies of a pregnant woman can also help protect her baby.
  • IgM
    IgM antibodies are the largest type of antibody. They are found in blood and lymph fluid and are the first type of antibody produced in response to an infection. They also cause other immune system cells to produce compounds that can destroy invading cells. IgM antibodies normally comprise about 5% to 10% of all the antibodies in the body.
  • IgD
    IgD antibodies are found in small amounts in the tissues that line the abdominal or chest cavity of the body. The function of IgD antibodies is not well-understood. They appear to play a role in allergic reactions to some substances such as milk, some medications, and some poisons.
  • IgE 
    IgE antibodies are found in the lungs, skin, and mucous membranes. They cause the body to react against foreign substances such as pollen, fungus spores, and animal dander. IgE antibody levels are often high in people with allergies.

Scientific Information

The benefits of colostrum to the human body – from boosting the immune system to promoting cell repair are continually being researched and discovered. To benefit fully from colostrum’s healing properties, your supplements should be of the highest purity – from a company that you can trust to collect only the freshest colostrum, and meticulously test for bioavailability.

Scientists and researchers have tested the healing properties of colostrum supplements with over 2,000 scientific studies:

  • Colostrum has been shown to prevent NSAID induced gut damage. NSAIDS are non-steroidal anti-inflammatory drugs given for the treatment of pain. They are a common cause of gastritis. Colostrum has also been shown to possibly have value in the treatment of other ulcerative conditions of the bowel.
  • Colostrum has been shown to enhance serum IGF-I, IgG, hormone and saliva IgA during athletes’ training. In clinical trials, IGF-1 is known to have strong anabolic effects on muscle tissue, as it is able to mimic most of the actions of growth hormone. Colostrum appears to aid strength and speed in athletes, plus increase insulin, which has anabolic effects.
  • Antibodies from colostrum in oral immunotherapy have aided treatment of various human infections, including those caused by antibiotic resistant bacteria.
  • Insulin-like growth factors I and II have been found in bovine colostrum. They stimulate the immune system; promote cell repair and growth; and affect how the body uses fat, protein and sugar. IGF-I is of benefit to athletes, body builders and people concerned about weight because it can help burn fat and encourage lean muscle tissue. IGF-I also has been shown to have improved blood sugar profiles in type II diabetics.
  • The immunoglobulins from colostrum were used successfully to treat diarrhea in HIV infected patients.
  • Bovine immunoglobulin concentrate may provide a new approach to the treatment and prevention of C difficle antibiotic associated with diarrhea and colitis.
  • Colostrum was used successfully to treat a Helicobacter pylori infection in infants in rural Bangladesh with immunoglobulins from hyper immune bovine colostrum.
  • Studies showed the efficacy of bovine milk immunoglobulin concentrate in preventing illness after Shigella flexneri Challenge. Most who are infected with Shigella develop diarrhea, fever, and stomach cramps after they are exposed to the bacterium.


1. What is colostrum?
Colostrum is the first lacteal secretions produced by a mammal prior to and just after giving birth. Colostrum is full of rich nutrients and immune factors that set babies on the path to health.

2. Why bovine colostrum?
Bovine colostrum is extremely similar to human colostrum in terms of digestibility and nutrients. At the same time, scientific studies have shown that colostrum’s highly prized immune and growth factors are found in greater quantities in bovine colostrum than in human.

3. Why is “first-milking” colostrum so important?
Colostrum taken from first-milking is colostrum that has been taken within the first day after the mother cow has given birth. First milking colostrum is critical because the number one factor for the quality of your colostrum is bioactivity – how much of the vital nutrients are complete. After 24 hours, the nutrient levels of colostrum drop considerably, as the secretion becomes closer to the composition of milk. In order to obtain the highest quality of nutrients, you need to collect the colostrum within a very careful time frame.

4. What are Grade “A” dairies?
Grade “A” dairies are dairy herds that follow the standards that the United States Department of Health sets down in the Milk Ordinance. Grade A dairies follow special standards in handling, processing and evaluation of their products all the way from raw to final product.

5. Do pasture-fed dairy cattle produce inferior colostrum, when compared to cows that are fed a healthy well balanced diet?
Successful U.S. Grade A dairies supply their cows a well balanced diet that includes multiple grain sources along with vitamin and mineral supplements. These diets definitely help to ensure that the colostrum and milk that is produced is of the highest quality. On the subject of pasture-fed cattle, we have not found any research that claims that pasture-fed cattle produce inferior colostrum. It’s important to note though, that with pasture-fed the possibility of environmental contaminants is a concern (such as pesticides, herbicides, and fungicides).

6. Is there any difference between powder and capsules?
Colostrum provides benefits whether taken in either powder or capsule form. The key is not the form that it comes in, but the bioavailability of the colostrum.

7. What is IgG?
IgG is one of the five main classes of immunoglobulins (Ig) or antibodies that participate in immune function. It is an antibacterial, antitoxic, and antiviral protein, and is the only class of antibodies to transfer through the placenta. High concentrations of IgG are present in quality colostrum, like Colstramax, which is concentrated through the removal of fat, casein, and lactose to contain a minimum of 25% IgG by total dry weight. It is important to note that IgG is just one of many valuable immune factors supplied in supplemental colostrum.

8. How is the potency of ADVAGEN’s colostrum compare with other products on the market?
The immune potency of colostrum is often determined by its IgG level, although many other important immune factors are also present in high-quality colostrum. For example, Colstramax, provides a minimum of 30% IgG by total dry weight. However, many colostrum manufacturers may claim 30% IgG, meaning that 30% of the total protein content is in the form of IgG (immunoglobulins are a type of protein). This can translate into as little as 20% IgG by total dry weight. Our colostrum is able to contain such high IgG concentration by removing the fat, casein, and lactose.

9. How can I find out quickly if the colostrum is of high quality?
You can do a taste test. Taste the colostrum powder and if it has a strong milk taste, then it is probably not quality colostrum since it contains high amounts of milk.

10. Will colostrum interfere with my other supplements or medications?
We have not uncovered any studies that show side effects with other medications. But it’s always a good idea to talk with a medical professional for advice regarding your medications and any changes to your regimen.

11. What quality control guidelines are followed for the collection and processing of colostrum?
There is a complete cGMP and HACCP program, which applies stringent controls on the dairies from which we collect our colostrum. CGMP (current Good Manufacturing Practice) and HACCP (Hazard Analysis and Critical Control Plan) are systems to help guarantee the safety of products. For more details, read about our quality control in Quality Processing.

12. Do I have to worry about possible pesticide or antibiotic contamination of the colostrum?
No, we are fortunate to draw all of our colostrum from U.S. dairies, whose safety and product quality are models for the rest of the world. Pesticide contamination of Grade A dairy cattle feed is tightly monitored and is not an issue for colostrum produced in the U.S. (Pesticide contaminated colostrum may be a concern for products produced outside the US). Antibiotic usage, especially beta-lactam usage (a form of antibiotics), is also tightly monitored. Beta-lactams are not allowed into the human milk supply, and hence not allowed in the human colostrum supply.

Dosage and Administration:

2 capsules twice daily on an empty stomach with 240ml of water or as directed by your physician.

Supplement Facts
Serving Size: 2 capsules
Serving Per Container: 60

Active Ingredient:

Bovine colostrum.


Vegetable cellulose and water.


450mg capsule in bottle of 120s.


Keep tightly closed in a dry place. Do not expose to excessive heat. Do not accept if seal is broken or missing.

Product from USA

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