{"id":2053,"date":"2023-10-11T03:03:51","date_gmt":"2023-10-11T03:03:51","guid":{"rendered":"https:\/\/advagen.com\/prebio\/?p=2053"},"modified":"2023-10-11T03:03:51","modified_gmt":"2023-10-11T03:03:51","slug":"gut-health-and-blood-pressure-hypertension-how-are-they-related","status":"publish","type":"post","link":"https:\/\/advagen.com\/prebio\/gut-health-and-blood-pressure-hypertension-how-are-they-related\/","title":{"rendered":"Gut Health and Blood Pressure (Hypertension): How Are They Related?"},"content":{"rendered":"<hr \/>\n<h3 style=\"text-align: left;\"><strong>Key Points:<\/strong><\/h3>\n<p style=\"text-align: left;\">\u2013 In 2021, the World Health Organization (WHO) has reported that around 1.28 billion adults aged 30-79 years worldwide have hypertension.<\/p>\n<p style=\"text-align: left;\">\u2013 The use of fiber to reduce blood pressure has been studied and published in various clinical trials.<\/p>\n<p style=\"text-align: left;\">\u2013 The effects of fiber on blood pressure lowering may have also been due to the gut microbiota. The gut microbiota ferments the undigested fiber (acting as prebiotics) that passes through to the large intestine, producing short-chain fatty acids (SCFAs) which activate receptors that play a part in blood pressure regulations.<\/p>\n<p style=\"text-align: left;\">\u2013 Other mechanisms include the regulation of genes related to immunity, inflammation and metabolism which may also affect blood pressure.<\/p>\n<hr \/>\n<h3 style=\"text-align: left;\">Introduction<\/h3>\n<p style=\"text-align: left;\"><strong>Hypertension<\/strong>, or\u00a0<strong>high blood pressure<\/strong>, is an increasingly prevalent condition worldwide. In 2021, the World Health Organization (WHO) has reported that around\u00a0<strong>1.28 billion adults aged 30-79 years worldwide<\/strong>\u00a0have hypertension, and less than half have it diagnosed and treated [1]. Some complications of high blood pressure include\u00a0<a href=\"https:\/\/fibrosol.com\/how-does-our-gut-health-affect-our-cardiovascular-system\/\">cardiovascular diseases<\/a>\u00a0such as heart attacks and strokes [1]. Often dubbed as the \u2018silent killer\u2019, this condition often shows no signs and symptoms [1].<\/p>\n<p style=\"text-align: left;\">Blood pressure reading is mainly divided into 2 numbers [2]:<\/p>\n<p style=\"text-align: left;\">\u2013\u00a0<strong>Systolic blood pressure<\/strong>\u00a0(i.e., the top number): this number indicates the pressure your blood is exerting against the blood vessels\u2019 walls when the heart beats<br \/>\n\u2013\u00a0<strong>Diastolic blood pressure<\/strong>\u00a0(i.e., the bottom number): this number indicates the pressure your blood is exerting against the blood vessels\u2019 walls when the heart relaxes between beats<\/p>\n<p style=\"text-align: left;\">With the incidence of hypertension on the rise, there is also an increasing awareness of how diet and other means can help with lowering the blood pressure naturally (i.e., without the use of medications). The implications of using\u00a0<a href=\"https:\/\/fibrosol.com\/health-benefits-of-dietary-fiber\/\">dietary fiber<\/a>\u00a0and their effects on blood pressure has garnered interest [3]. How does the use of dietary fiber help with lowering blood pressure? Does the fiber affect blood pressure directly or through other mechanisms, such as via its interactions with the gut microbiota?<\/p>\n<p style=\"text-align: left;\"><strong>World Hypertension Day<\/strong>\u00a0falls on 17 May every year. In conjunction with this day, find out how the health of your gut and dietary fiber intake is implicated in your blood pressure readings!<\/p>\n<h3 style=\"text-align: left;\">How Fiber Intake affects Blood Pressure<\/h3>\n<p style=\"text-align: left;\"><a href=\"https:\/\/fibrosol.com\/health-benefits-of-dietary-fiber\/\">Fiber<\/a>\u00a0is a form of carbohydrates, naturally present in plants. Although most carbohydrates can be broken down by the body\u2019s enzyme into simple sugars, our body is unable to completely break down fibers and gets passed through to the large intestine. It is generally divided into 2 forms:\u00a0<strong>soluble<\/strong>\u00a0and\u00a0<strong>insoluble<\/strong>\u00a0fibers [4].<\/p>\n<p style=\"text-align: left;\">The use of fiber to reduce blood pressure has been studied and published in various clinical trials. A meta-analysis done in 2005 aggregated data from 24 different studies and trials to see the effects of fiber on blood pressure [5]. This study found that fiber supplementation at\u00a0<strong>11.5g per day<\/strong>\u00a0caused a non-significant decrease in systolic blood pressure and a significant change in diastolic blood pressure, with effects larger for\u00a0<strong>older<\/strong>\u00a0and\u00a0<strong>hypertensive<\/strong>\u00a0populations [5].<\/p>\n<p style=\"text-align: left;\">The authors of the study also concluded that increasing fiber intake in the general population may contribute to prevention of hypertension [5], especially as the intake of dietary fiber in the general population is low [6]. A high-fiber diet was also found to have experienced a\u00a0<strong>15% reduction in systolic blood pressure<\/strong>, along with an inverse risk of developing cardiovascular diseases [7].<\/p>\n<h3 style=\"text-align: left;\">How Gut Microbiota affects Blood Pressure<\/h3>\n<p style=\"text-align: left;\">The effects of fiber on blood pressure lowering may have also been due to the presence of the microorganism environment in the gut, which is also termed as your\u00a0<a href=\"https:\/\/fibrosol.com\/what-is-the-gut-microbiota\/\">gut microbiota<\/a>. The\u00a0<strong>gut microbiota<\/strong>\u00a0consists of a range of microorganisms consisting of bacteria, virus, and fungi [8], and the composition differs depending on several factors such as environmental and lifestyle reasons (e.g., diet) [9].<\/p>\n<p style=\"text-align: left;\">The gut microbiota ferments the undigested fiber that passes through to the large intestine, producing\u00a0<strong>short-chain fatty acids (SCFAs)<\/strong>\u00a0and gases. These SCFAs produced by the breakdown of fiber by the gut microbiota play important roles in multiple body functions, one of which includes the modulation of blood pressure and decreasing the risk of developing hypertension from a fiber-rich diet [10].\u00a0<strong>Dysbiosis<\/strong>\u00a0of the gut (i.e., alterations of the gut microbiota) is also found to be linked with hypertension [11].<\/p>\n<p style=\"text-align: left;\">There are many mechanisms on how the gut microbiota and its derivatives affect the blood pressure [12]:<\/p>\n<p style=\"text-align: left;\">\u2013\u00a0<strong>SCFAs<\/strong>\u00a0produced from the fermentation of the fibers activates receptors that play a part in blood pressure regulations<br \/>\n\u2013 Reduction in\u00a0<strong>microbial gene richness<\/strong>\u00a0may also lead to inflammation, which can also be a cause of high blood pressure<br \/>\n\u2013 Gut microbiota can influence the production of chemicals by gastrointestinal cells, which has effects on the\u00a0<a href=\"https:\/\/fibrosol.com\/gut-brain-immune-axis-an-introduction\/\"><strong>gut-brain axis<\/strong><\/a><br \/>\n\u2013 Gut microbiota may also regulate genes related to immunity, inflammation and metabolism which may also affect blood pressure<\/p>\n<h3 style=\"text-align: left;\">Conclusion<\/h3>\n<p style=\"text-align: left;\">Hypertension, often termed as the \u2018silent killer\u2019, often presents with no symptoms, and affects more than 1 billion of adults worldwide. It has severe complications if it goes undetected and untreated, including heart attacks and strokes. There has been much interest in natural ways such as the use of diet and dietary fiber in managing and lowering blood pressure. The use of fiber has also been touted to be able to reduce blood pressure, with potential effects due to the\u00a0<a href=\"https:\/\/fibrosol.com\/what-is-the-gut-microbiota\/\">gut microbiota<\/a>. Importance of the gut microbiota on blood pressure could also have been mediated by other factors such as its effects on the immunity and metabolism of the individual.<\/p>\n<p style=\"text-align: left;\"><em>This article is written in conjunction with World Hypertension Day, which falls on 17 May every year.<\/em><\/p>\n<h3 style=\"text-align: left;\">Related Articles<\/h3>\n<p style=\"text-align: left;\"><a href=\"https:\/\/fibrosol.com\/tips-on-increasing-dietary-fiber-intake\/\"><img decoding=\"async\" class=\"alignnone size-medium wp-image-1178\" src=\"https:\/\/fibrosol.com\/wp-content\/uploads\/2021\/09\/Fibrosol-website-featured-image-1-300x155.jpg\" sizes=\"(max-width: 300px) 100vw, 300px\" srcset=\"https:\/\/fibrosol.com\/wp-content\/uploads\/2021\/09\/Fibrosol-website-featured-image-1-300x155.jpg 300w, https:\/\/fibrosol.com\/wp-content\/uploads\/2021\/09\/Fibrosol-website-featured-image-1-1024x530.jpg 1024w, https:\/\/fibrosol.com\/wp-content\/uploads\/2021\/09\/Fibrosol-website-featured-image-1-768x397.jpg 768w, https:\/\/fibrosol.com\/wp-content\/uploads\/2021\/09\/Fibrosol-website-featured-image-1-1536x794.jpg 1536w, https:\/\/fibrosol.com\/wp-content\/uploads\/2021\/09\/Fibrosol-website-featured-image-1.jpg 1920w\" alt=\"dietary fiber signboard dietary fibre, fruits and vegetables\" width=\"300\" height=\"155\" \/><br \/>\n6 Tips on Increasing Dietary Fiber Intake<\/a><\/p>\n<p style=\"text-align: left;\"><a href=\"https:\/\/fibrosol.com\/gut-brain-immune-axis-an-introduction\/\"><img decoding=\"async\" class=\"alignnone size-medium wp-image-1318\" src=\"https:\/\/fibrosol.com\/wp-content\/uploads\/2022\/06\/Gut-Brain-Immune-axis-v1-300x155.jpg\" sizes=\"(max-width: 300px) 100vw, 300px\" srcset=\"https:\/\/fibrosol.com\/wp-content\/uploads\/2022\/06\/Gut-Brain-Immune-axis-v1-300x155.jpg 300w, https:\/\/fibrosol.com\/wp-content\/uploads\/2022\/06\/Gut-Brain-Immune-axis-v1-1024x530.jpg 1024w, https:\/\/fibrosol.com\/wp-content\/uploads\/2022\/06\/Gut-Brain-Immune-axis-v1-768x397.jpg 768w, https:\/\/fibrosol.com\/wp-content\/uploads\/2022\/06\/Gut-Brain-Immune-axis-v1-1536x794.jpg 1536w, https:\/\/fibrosol.com\/wp-content\/uploads\/2022\/06\/Gut-Brain-Immune-axis-v1.jpg 1920w\" alt=\"gut-brain-immune axis family photo\" width=\"300\" height=\"155\" \/><br \/>\nGut-Brain-Immune Axis: An Introduction<\/a><\/p>\n<p style=\"text-align: left;\"><a href=\"https:\/\/fibrosol.com\/what-is-the-gut-microbiota\/\"><img decoding=\"async\" class=\"alignnone size-medium wp-image-1390\" src=\"https:\/\/fibrosol.com\/wp-content\/uploads\/2021\/11\/What-is-gut-microbiota-300x155.jpg\" sizes=\"(max-width: 300px) 100vw, 300px\" srcset=\"https:\/\/fibrosol.com\/wp-content\/uploads\/2021\/11\/What-is-gut-microbiota-300x155.jpg 300w, https:\/\/fibrosol.com\/wp-content\/uploads\/2021\/11\/What-is-gut-microbiota-1024x530.jpg 1024w, https:\/\/fibrosol.com\/wp-content\/uploads\/2021\/11\/What-is-gut-microbiota-768x397.jpg 768w, https:\/\/fibrosol.com\/wp-content\/uploads\/2021\/11\/What-is-gut-microbiota-1536x794.jpg 1536w, https:\/\/fibrosol.com\/wp-content\/uploads\/2021\/11\/What-is-gut-microbiota.jpg 1920w\" alt=\"What is the gut microbiota\" width=\"300\" height=\"155\" \/><br \/>\nWhat is the Gut Microbiota?<\/a><\/p>\n<h3 style=\"text-align: left;\">References<\/h3>\n<ol>\n<li style=\"text-align: left;\"><a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hypertension\">World Health Organization. Hypertension. 2021 August.<\/a><\/li>\n<li style=\"text-align: left;\"><a href=\"https:\/\/www.heart.org\/en\/health-topics\/high-blood-pressure\/understanding-blood-pressure-readings\">American Heart Association (AHA). Understanding Blood Pressure Readings.<\/a><\/li>\n<li style=\"text-align: left;\"><a href=\"https:\/\/www.webmd.com\/hypertension-high-blood-pressure\/news\/20050304\/high-fiber-diet-may-fight-high-blood-pressure\">High-Fiber Diet May Fight High Blood Pressure. 2005.<\/a><\/li>\n<li style=\"text-align: left;\"><a href=\"https:\/\/fibrosol.com\/fiber\/\">Fiber. 2020. Fibrosol.com<\/a><\/li>\n<li style=\"text-align: left;\"><a href=\"https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/fullarticle\/486375\">Streppel MT, Arends LR, van \u2019t Veer P, et al. Dietary Fiber and Blood Pressure: A Meta-analysis of Randomized Placebo-Controlled Trials.\u00a0<em>Arch Intern Med<\/em>. 2005;165(2):150\u2013156.<\/a><\/li>\n<li style=\"text-align: left;\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7032538\/\">Hartley L, May MD, Loveman E, et al. Dietary fibre for the primary prevention of cardiovascular disease.\u00a0<em>Cochrane Database Syst Rev<\/em>. 2016;2016(1):CD011472.<\/a><\/li>\n<li style=\"text-align: left;\"><a href=\"https:\/\/www.eurekalert.org\/news-releases\/717892\">EurekAlert! Science News Release. American College of Cardiology. High fiber diet associated with reduced CV risk in hypertension, type 2 diabetes patients. 2019 Oct.<\/a><\/li>\n<li style=\"text-align: left;\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5433529\/\">Thursby E, Juge N. Introduction to the human gut microbiota.\u00a0<em>Biochem J<\/em>. 2017;474(11):1823-1836.<\/a><\/li>\n<li style=\"text-align: left;\"><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2020.604179\/full\">Rutsch A, Kantsj\u00f6 JB., Ronchi F. The Gut-Brain Axis: How Microbiota and Host Inflammasome Influence Brain Physiology and Pathology.\u00a0<em>Immunol<\/em>. 2020;11.<\/a><\/li>\n<li style=\"text-align: left;\"><a href=\"https:\/\/link.springer.com\/article\/10.1007\/s11906-017-0734-1\">Richards E.M., Pepine C.J., Raizada M.K. et al. The Gut, Its Microbiome, and Hypertension.\u00a0<em>Curr Hypertens Rep. 2017;<\/em>19:36.<\/a><\/li>\n<li style=\"text-align: left;\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4433416\/\">Yang T, Santisteban MM, Rodriguez V, et al. Gut dysbiosis is linked to hypertension.\u00a0<em>Hypertension<\/em>. 2015 Jun;65(6):1331-40.<\/a><\/li>\n<li style=\"text-align: left;\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4578629\/\">Jose PA, Raj D. Gut microbiota in hypertension.\u00a0<em>Curr Opin Nephrol Hypertens<\/em>. 2015;24(5):403-409.<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Key Points: \u2013 In 2021, the World Health Organization (WHO) has reported that around 1.28 billion adults aged 30-79 years worldwide have hypertension. \u2013 The use of fiber to reduce blood pressure has been studied and published in various clinical trials. \u2013 The effects of fiber on blood pressure lowering may have also been due [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":2054,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_eb_attr":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[3],"tags":[],"class_list":["post-2053","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles"],"blocksy_meta":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Gut Health and Blood Pressure (Hypertension): How Are They Related? 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