{"id":2010,"date":"2023-10-11T02:40:11","date_gmt":"2023-10-11T02:40:11","guid":{"rendered":"https:\/\/advagen.com\/prebio\/?p=2010"},"modified":"2023-10-11T02:42:21","modified_gmt":"2023-10-11T02:42:21","slug":"how-prebiotics-help-lower-the-risk-of-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/","title":{"rendered":"How Prebiotics Help Lower The Risk Of Alzheimer\u2019s Disease"},"content":{"rendered":"
\n

Key Points:<\/strong><\/h3>\n

\u2013 Over 55 million people around the world are estimated to be living with dementia, with Alzheimer\u2019s Disease (AD) being the most common type.<\/p>\n

\u2013 Although the exact causes of AD have yet to be fully established, amyloid and tau proteins are found to accumulate in the brain of patients with AD. Neuroinflammation is also often a key element in AD.<\/p>\n

\u2013 Health of our gut microbiota is associated with AD. Harmful bacteria may worsen neuroinflammation, while metabolites from beneficial gut bacteria may help protect against it.<\/p>\n

\u2013 Prebiotics could be used to enhance and regulate the health of the gut microbiota, thereby lowering the risk of developing AD.<\/p>\n

\n

Over\u00a055 million people<\/strong>\u00a0around the world are estimated to be living with\u00a0dementia<\/strong>\u00a0in 2020. This number is likely to double every 20 years, reaching a total of 78 million by the year 2030 [1]. The most common type of dementia is Alzheimer\u2019s Disease (AD). We have discussed how dietary fiber may have effects on\u00a0dementia<\/a>\u00a0based on a Japanese study done recently which found that a high intake of dietary soluble fiber is linked to a lower risk of developing disabling dementia [2]. Most\u00a0prebiotics<\/strong><\/a>\u00a0are\u00a0dietary fibers<\/a>.\u00a0However, not all dietary fibers are prebiotics. Read on to find out more about the effects of prebiotics and gut microbiota on dementia and Alzheimer\u2019s disease.<\/p>\n

Prebiotics and Gut Microbiota<\/h3>\n

Our gut consists of trillions of such microorganisms including bacteria, viruses, fungi and protozoa species. This composition of microorganisms residing in our gut is collectively termed\u00a0gut microbiota<\/strong>, which is unique to everyone. It varies due to several factors, such as\u00a0environmental<\/strong>,\u00a0lifestyle<\/strong>,\u00a0dietary habits<\/strong>, and consumption of medications such as\u00a0antibiotics<\/strong>\u00a0[3].<\/p>\n

This innate set of gut microbiota (the set that we are born with) is thought to be the most optimum for oneself. This optimum composition deteriorates as we age. Along with poorer modern-day diets lacking in prebiotics (i.e., food for the beneficial gut bacteria) as well as increased use of medications, the composition and amount of good gut bacteria decrease even faster.<\/p>\n

Prebiotics are defined by the\u00a0International Scientific Association for Probiotics and Prebiotics (ISAPP)<\/strong><\/a>\u00a0as a substrate that is\u00a0selectively utilized<\/strong>\u00a0by\u00a0host microorganisms<\/strong>\u00a0conferring a\u00a0health benefit<\/strong>\u00a0[4]. In loose terms, prebiotics are food for the beneficial gut bacteria in a process called fermentation. This feeding process produces metabolites such as\u00a0short-chain fatty acids (SCFAs)<\/strong>\u00a0which confer health benefits to us. One such health benefit could be healthy aging.<\/p>\n

Gut Microbiota and Alzheimer\u2019s Disease<\/h3>\n

Although the exact causes of AD have yet to be fully established, it has been found that various types of proteins (e.g.,\u00a0amyloid<\/strong>\u00a0and\u00a0tau proteins<\/strong>) accumulate in the brains of patients with AD [5].\u00a0Neuroinflammation<\/strong>\u00a0is also a key element in the accumulation of amyloid hence the progression of AD [6].<\/p>\n

The\u00a0health of our gut microbiota<\/strong>\u00a0is associated with AD. The gut microbiota and the brain communicate bi-directionally, and this interaction has been termed the\u00a0gut-brain axis<\/a>\u00a0[7]. Dysbiosis, which refers to an altered gut microbiota, has been associated with various neurodegenerative diseases including AD. Reduction in microbial diversity has been observed in patients with AD as compared to patients without [8].<\/p>\n

Harmful gut bacteria may even produce\u00a0amyloid peptides<\/strong>, which can enter the bloodstream due to\u00a0increased gut permeability<\/strong>. These peptides can then cross the blood-brain barrier and accumulate amyloid in the brain, further exacerbating AD [9]. Metabolites produced from harmful bacteria can also\u00a0worsen neuroinflammation<\/strong>\u00a0in the brain, while metabolites (such as SCFAs) produced from beneficial gut bacteria may help protect against AD by inhibiting the aggregation of amyloid peptides and maintaining cognitive functions [9,10].<\/p>\n

How Prebiotics Can Help with Alzheimer\u2019s Disease<\/h3>\n

Prebiotics are food selectively utilized by beneficial gut bacteria. By taking prebiotics, we improve the health of our gut microbiota by allowing the\u00a0beneficial bacteria to grow<\/strong>\u00a0and proliferate, at the same time\u00a0crowding out the harmful ones<\/strong>. This may help to ameliorate the risk factors of AD such as\u00a0gut permeability<\/strong>,\u00a0amyloid peptides<\/strong>, and\u00a0systemic inflammation<\/strong>\u00a0[9].<\/p>\n

Conclusion<\/h3>\n

There is currently no cure for AD. Current evidence points to the importance of the gut microbiota as a modulator of neurodegenerative diseases such as AD. The gut microbiota serves as a promising therapeutic target for the prevention and treatment of AD. Prebiotics could potentially be used to enhance and regulate the health of the gut microbiota, thereby lowering the risks of neurodegenerative diseases.<\/p>\n

Related articles<\/h3>\n

\"fiber
\nDietary Fiber and Its Links To Dementia<\/a><\/p>\n

\"Prebiotic
\nPrebiotic: Gut Microbiota, Gut Health, and Beyond<\/a><\/p>\n

\"What
\nWhat is the Gut Microbiota?<\/a><\/p>\n

References<\/h3>\n
    \n
  1. Alzheimer\u2019s Disease International. Dementia Statistics.<\/a><\/li>\n
  2. Yamagishi K, Maruyama K, Ikeda A, et al. Dietary fiber intake and risk of incident disabling dementia: the Circulatory Risk in Communities Study.\u00a0Nutr Neurosci<\/em>. 2022 Feb 6:1-8.<\/a><\/li>\n
  3. Rutsch A, Kantsj\u00f6 JB., Ronchi F. The Gut-Brain Axis: How Microbiota and Host Inflammasome Influence Brain Physiology and Pathology.\u00a0Immunol<\/em>. 2020;11.<\/a><\/li>\n
  4. Gibson, G., Hutkins, R., Sanders, M. et al. Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics.\u00a0Nat Rev Gastroenterol Hepatol<\/em>. 2017;14:491\u2013502.<\/a><\/li>\n
  5. Bloom GS. Amyloid-\u03b2 and tau: the trigger and bullet in Alzheimer disease pathogenesis.\u00a0JAMA Neurol<\/em>. 2014 Apr;71(4):505-8.<\/a><\/li>\n
  6. Cerovic M, Forloni G, Balducci C. Neuroinflammation and the Gut Microbiota: Possible Alternative Therapeutic Targets to Counteract Alzheimer\u2019s Disease?\u00a0Front Aging Neurosci<\/em>. 2019 Oct 18;11:284.<\/a><\/li>\n
  7. Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems.\u00a0Ann Gastroenterol<\/em>. 2015;28(2):203-209.<\/a><\/li>\n
  8. Vogt NM, Kerby RL, Dill-McFarland KA, et al. Gut microbiome alterations in Alzheimer\u2019s disease.\u00a0Sci Rep<\/em>. 2017 Oct 19;7(1):13537.<\/a><\/li>\n
  9. D\u2019Argenio V, Sarnataro D. Probiotics, prebiotics and their role in Alzheimer\u2019s disease.\u00a0Neural Regen Res<\/em>. 2021 Sep;16(9):1768-1769.<\/a><\/li>\n
  10. Ho L, Ono K, Tsuji M, et al. Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer\u2019s disease-type beta-amyloid neuropathological mechanisms.\u00a0Expert Rev Neurother<\/em>. 2018 Jan;18(1):83-90.<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Key Points: \u2013 Over 55 million people around the world are estimated to be living with dementia, with Alzheimer\u2019s Disease (AD) being the most common type. \u2013 Although the exact causes of AD have yet to be fully established, amyloid and tau proteins are found to accumulate in the brain of patients with AD. Neuroinflammation […]<\/p>\n","protected":false},"author":4,"featured_media":2011,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_eb_attr":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[3],"tags":[],"class_list":["post-2010","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles"],"blocksy_meta":[],"yoast_head":"\nHow Prebiotics Help Lower The Risk Of Alzheimer\u2019s Disease - ADVAGEN Prebio | bowel regularity & good gut bacteria<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"How Prebiotics Help Lower The Risk Of Alzheimer\u2019s Disease - ADVAGEN Prebio | bowel regularity & good gut bacteria\" \/>\n<meta property=\"og:description\" content=\"Key Points: \u2013 Over 55 million people around the world are estimated to be living with dementia, with Alzheimer\u2019s Disease (AD) being the most common type. \u2013 Although the exact causes of AD have yet to be fully established, amyloid and tau proteins are found to accumulate in the brain of patients with AD. Neuroinflammation […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/\" \/>\n<meta property=\"og:site_name\" content=\"ADVAGEN Prebio | bowel regularity & good gut bacteria\" \/>\n<meta property=\"article:published_time\" content=\"2023-10-11T02:40:11+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-10-11T02:42:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/advagen.com\/prebio\/wp-content\/uploads\/2023\/10\/Prebiotics-x-AD-featured-image.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"993\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"ADVAGEN ADVAGEN\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"ADVAGEN ADVAGEN\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/\"},\"author\":{\"name\":\"ADVAGEN ADVAGEN\",\"@id\":\"https:\/\/advagen.com\/prebio\/#\/schema\/person\/53573f6c513e3ee6542b683d20761eaa\"},\"headline\":\"How Prebiotics Help Lower The Risk Of Alzheimer\u2019s Disease\",\"datePublished\":\"2023-10-11T02:40:11+00:00\",\"dateModified\":\"2023-10-11T02:42:21+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/\"},\"wordCount\":974,\"publisher\":{\"@id\":\"https:\/\/advagen.com\/prebio\/#organization\"},\"image\":{\"@id\":\"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/advagen.com\/prebio\/wp-content\/uploads\/2023\/10\/Prebiotics-x-AD-featured-image.jpg\",\"articleSection\":[\"Articles\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/\",\"url\":\"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/\",\"name\":\"How Prebiotics Help Lower The Risk Of Alzheimer\u2019s Disease - ADVAGEN Prebio | bowel regularity & good gut bacteria\",\"isPartOf\":{\"@id\":\"https:\/\/advagen.com\/prebio\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/advagen.com\/prebio\/wp-content\/uploads\/2023\/10\/Prebiotics-x-AD-featured-image.jpg\",\"datePublished\":\"2023-10-11T02:40:11+00:00\",\"dateModified\":\"2023-10-11T02:42:21+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/#primaryimage\",\"url\":\"https:\/\/advagen.com\/prebio\/wp-content\/uploads\/2023\/10\/Prebiotics-x-AD-featured-image.jpg\",\"contentUrl\":\"https:\/\/advagen.com\/prebio\/wp-content\/uploads\/2023\/10\/Prebiotics-x-AD-featured-image.jpg\",\"width\":1920,\"height\":993},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/advagen.com\/prebio\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"How Prebiotics Help Lower The Risk Of Alzheimer\u2019s Disease\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/advagen.com\/prebio\/#website\",\"url\":\"https:\/\/advagen.com\/prebio\/\",\"name\":\"ADVAGEN Prebio | bowel regularity & good gut bacteria\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/advagen.com\/prebio\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/advagen.com\/prebio\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/advagen.com\/prebio\/#organization\",\"name\":\"ADVAGEN Prebio | bowel regularity & good gut bacteria\",\"url\":\"https:\/\/advagen.com\/prebio\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/advagen.com\/prebio\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/advagen.com\/prebio\/wp-content\/uploads\/2025\/10\/ADVAGEN-Prebio-Color-Logo-Bold-B-Arial-02-scaled.png\",\"contentUrl\":\"https:\/\/advagen.com\/prebio\/wp-content\/uploads\/2025\/10\/ADVAGEN-Prebio-Color-Logo-Bold-B-Arial-02-scaled.png\",\"width\":1920,\"height\":850,\"caption\":\"ADVAGEN Prebio | bowel regularity & good gut bacteria\"},\"image\":{\"@id\":\"https:\/\/advagen.com\/prebio\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/advagen.com\/prebio\/#\/schema\/person\/53573f6c513e3ee6542b683d20761eaa\",\"name\":\"ADVAGEN ADVAGEN\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/secure.gravatar.com\/avatar\/593927d89aa752535c89e2ac1f1ba4fa182ee76ec10a9c7b4c61e9f9fe16a04d?s=96&d=mm&r=g\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/593927d89aa752535c89e2ac1f1ba4fa182ee76ec10a9c7b4c61e9f9fe16a04d?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/593927d89aa752535c89e2ac1f1ba4fa182ee76ec10a9c7b4c61e9f9fe16a04d?s=96&d=mm&r=g\",\"caption\":\"ADVAGEN ADVAGEN\"},\"url\":\"https:\/\/advagen.com\/prebio\/author\/advagen\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"How Prebiotics Help Lower The Risk Of Alzheimer\u2019s Disease - ADVAGEN Prebio | bowel regularity & good gut bacteria","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/","og_locale":"en_US","og_type":"article","og_title":"How Prebiotics Help Lower The Risk Of Alzheimer\u2019s Disease - ADVAGEN Prebio | bowel regularity & good gut bacteria","og_description":"Key Points: \u2013 Over 55 million people around the world are estimated to be living with dementia, with Alzheimer\u2019s Disease (AD) being the most common type. \u2013 Although the exact causes of AD have yet to be fully established, amyloid and tau proteins are found to accumulate in the brain of patients with AD. Neuroinflammation […]","og_url":"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/","og_site_name":"ADVAGEN Prebio | bowel regularity & good gut bacteria","article_published_time":"2023-10-11T02:40:11+00:00","article_modified_time":"2023-10-11T02:42:21+00:00","og_image":[{"width":1920,"height":993,"url":"https:\/\/advagen.com\/prebio\/wp-content\/uploads\/2023\/10\/Prebiotics-x-AD-featured-image.jpg","type":"image\/jpeg"}],"author":"ADVAGEN ADVAGEN","twitter_card":"summary_large_image","twitter_misc":{"Written by":"ADVAGEN ADVAGEN","Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/#article","isPartOf":{"@id":"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/"},"author":{"name":"ADVAGEN ADVAGEN","@id":"https:\/\/advagen.com\/prebio\/#\/schema\/person\/53573f6c513e3ee6542b683d20761eaa"},"headline":"How Prebiotics Help Lower The Risk Of Alzheimer\u2019s Disease","datePublished":"2023-10-11T02:40:11+00:00","dateModified":"2023-10-11T02:42:21+00:00","mainEntityOfPage":{"@id":"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/"},"wordCount":974,"publisher":{"@id":"https:\/\/advagen.com\/prebio\/#organization"},"image":{"@id":"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/#primaryimage"},"thumbnailUrl":"https:\/\/advagen.com\/prebio\/wp-content\/uploads\/2023\/10\/Prebiotics-x-AD-featured-image.jpg","articleSection":["Articles"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/","url":"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/","name":"How Prebiotics Help Lower The Risk Of Alzheimer\u2019s Disease - ADVAGEN Prebio | bowel regularity & good gut bacteria","isPartOf":{"@id":"https:\/\/advagen.com\/prebio\/#website"},"primaryImageOfPage":{"@id":"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/#primaryimage"},"image":{"@id":"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/#primaryimage"},"thumbnailUrl":"https:\/\/advagen.com\/prebio\/wp-content\/uploads\/2023\/10\/Prebiotics-x-AD-featured-image.jpg","datePublished":"2023-10-11T02:40:11+00:00","dateModified":"2023-10-11T02:42:21+00:00","breadcrumb":{"@id":"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/#primaryimage","url":"https:\/\/advagen.com\/prebio\/wp-content\/uploads\/2023\/10\/Prebiotics-x-AD-featured-image.jpg","contentUrl":"https:\/\/advagen.com\/prebio\/wp-content\/uploads\/2023\/10\/Prebiotics-x-AD-featured-image.jpg","width":1920,"height":993},{"@type":"BreadcrumbList","@id":"https:\/\/advagen.com\/prebio\/how-prebiotics-help-lower-the-risk-of-alzheimers-disease\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/advagen.com\/prebio\/"},{"@type":"ListItem","position":2,"name":"How Prebiotics Help Lower The Risk Of Alzheimer\u2019s Disease"}]},{"@type":"WebSite","@id":"https:\/\/advagen.com\/prebio\/#website","url":"https:\/\/advagen.com\/prebio\/","name":"ADVAGEN Prebio | bowel regularity & good gut bacteria","description":"","publisher":{"@id":"https:\/\/advagen.com\/prebio\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/advagen.com\/prebio\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/advagen.com\/prebio\/#organization","name":"ADVAGEN Prebio | bowel regularity & good gut bacteria","url":"https:\/\/advagen.com\/prebio\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/advagen.com\/prebio\/#\/schema\/logo\/image\/","url":"https:\/\/advagen.com\/prebio\/wp-content\/uploads\/2025\/10\/ADVAGEN-Prebio-Color-Logo-Bold-B-Arial-02-scaled.png","contentUrl":"https:\/\/advagen.com\/prebio\/wp-content\/uploads\/2025\/10\/ADVAGEN-Prebio-Color-Logo-Bold-B-Arial-02-scaled.png","width":1920,"height":850,"caption":"ADVAGEN Prebio | bowel regularity & good gut bacteria"},"image":{"@id":"https:\/\/advagen.com\/prebio\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/advagen.com\/prebio\/#\/schema\/person\/53573f6c513e3ee6542b683d20761eaa","name":"ADVAGEN ADVAGEN","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/593927d89aa752535c89e2ac1f1ba4fa182ee76ec10a9c7b4c61e9f9fe16a04d?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/593927d89aa752535c89e2ac1f1ba4fa182ee76ec10a9c7b4c61e9f9fe16a04d?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/593927d89aa752535c89e2ac1f1ba4fa182ee76ec10a9c7b4c61e9f9fe16a04d?s=96&d=mm&r=g","caption":"ADVAGEN ADVAGEN"},"url":"https:\/\/advagen.com\/prebio\/author\/advagen\/"}]}},"_links":{"self":[{"href":"https:\/\/advagen.com\/prebio\/wp-json\/wp\/v2\/posts\/2010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/advagen.com\/prebio\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/advagen.com\/prebio\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/advagen.com\/prebio\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/advagen.com\/prebio\/wp-json\/wp\/v2\/comments?post=2010"}],"version-history":[{"count":4,"href":"https:\/\/advagen.com\/prebio\/wp-json\/wp\/v2\/posts\/2010\/revisions"}],"predecessor-version":[{"id":2015,"href":"https:\/\/advagen.com\/prebio\/wp-json\/wp\/v2\/posts\/2010\/revisions\/2015"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/advagen.com\/prebio\/wp-json\/wp\/v2\/media\/2011"}],"wp:attachment":[{"href":"https:\/\/advagen.com\/prebio\/wp-json\/wp\/v2\/media?parent=2010"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/advagen.com\/prebio\/wp-json\/wp\/v2\/categories?post=2010"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/advagen.com\/prebio\/wp-json\/wp\/v2\/tags?post=2010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}