{"version":"1.0","provider_name":"ADVAGEN+ BFL100 | Good gut bacteria","provider_url":"https:\/\/advagen.com\/bfl100","author_name":"ADVAGEN ADVAGEN","author_url":"https:\/\/advagen.com\/bfl100\/author\/advagen\/","title":"Prebiotic: Gut Microbiota, Gut Health, and Beyond - ADVAGEN+ BFL100 | Good gut bacteria","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"CTzxujJOyN\"><a href=\"https:\/\/advagen.com\/bfl100\/prebiotic-gut-microbiota-gut-health-and-beyond\/\">Prebiotic: Gut Microbiota, Gut Health, and Beyond<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/advagen.com\/bfl100\/prebiotic-gut-microbiota-gut-health-and-beyond\/embed\/#?secret=CTzxujJOyN\" width=\"600\" height=\"338\" title=\"&#8220;Prebiotic: Gut Microbiota, Gut Health, and Beyond&#8221; &#8212; ADVAGEN+ BFL100 | Good gut bacteria\" data-secret=\"CTzxujJOyN\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script type=\"text\/javascript\">\n\/* <![CDATA[ *\/\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/* ]]> *\/\n<\/script>\n","thumbnail_url":"https:\/\/advagen.com\/bfl100\/wp-content\/uploads\/2023\/10\/Prebiotics-educational-post-featured-image.jpg","thumbnail_width":1920,"thumbnail_height":993,"description":"Key Points: \u2013 A \u2018prebiotic\u2019 is often loosely thought of as the \u2018food for the probiotics\u2019. \u2013 This innate gut microbiota is supposedly thought to be the best that nature has offered us, and various factors such as the use of antibiotics and natural aging lead to the decrease in the composition and amount of beneficial gut bacteria, which ultimately negatively affects gut health. \u2013 A prebiotic is defined as by ISAPP as a substrate that is selectively utilized by host microorganisms conferring a health benefit. \u2013 Prebiotics serve as a form of fuel for the gut microbiota, producing metabolites such as short-chain fatty acids (SCFAs) that confer certain health benefits to us. \u2013 Prebiotics can also aid in maximizing the effects of your probiotic supplements. Introduction There has been an increasing understanding and awareness of\u00a0prebiotic, as people are starting to look for diets and foods that are linked with health benefits. There may be a general understanding of what a \u2018prebiotic\u2019 is: loosely thought of as the \u2018food for the probiotics\u2019. However, many do not know what exactly it is, how is it considered and classified as a prebiotic, what are the types of food that contains it, or the health benefits it can provide. Other than prebiotics, there is also increasing awareness of the importance of gut health and its effects on other parts of the body, such as the\u00a0brain, nervous system, and the immune system. How can prebiotics help in improving our\u00a0gut health? Does it have any effect on our innate and unique set of gut microbiota? How does it complement with the more commonly known probiotics? Read on to find out more about prebiotics and understand why there is an increasing awareness to them. What is the innate gut microbiota? To better understand prebiotics and their functions, we need to first look at what is the\u00a0gut microbiota\u00a0(also called\u00a0gut microbiome\u00a0in certain literature). The gut microbiota consists of different types of microorganisms such as bacteria, viruses, and fungi, and the number of bacterial cells is estimated to outnumber our human cells by about 10 times [1]. Everyone has a unique set of innate (inborn, natural) gut microbiota, due to the differences in many factors that can affect the composition of the microbes, such as the use of\u00a0antibiotics,\u00a0environmental,\u00a0lifestyle\u00a0and\u00a0diet\u00a0factors [2]. This innate gut microbiota is supposedly thought to be the best that nature has offered us, and various factors such as the use of antibiotics and natural aging lead to the decrease in the composition and amount of beneficial gut bacteria, which ultimately negatively affects gut health. The gut microbiota does not affect just the gut health but is also involved in the health of many other body systems. Firstly, the gut microbiota has effects on our\u00a0mental health\u00a0[3], and it is thought to be affected via the\u00a0gut-brain axis\u00a0[4]. It may also affect\u00a0cardiovascular health, including coronary artery disease and heart failure [5]. The gut microbiota can also affect our\u00a0immune system\u00a0and\u00a0inflammation\u00a0pathways [6]. Other benefits include supporting our\u00a0blood sugar\u00a0[7],\u00a0blood pressure\u00a0[8],\u00a0cholesterol\u00a0levels [9] and\u00a0respiratory health\u00a0[10]. This goes to show that the health of our gut microbiota is deeply associated with our general health and well-being. There is a need to maintain this healthy level of innate gut microbiota for it to contribute to our overall health and well-being. How do we ensure that we have a healthy composition, level, and diversity of gut microbiota? This is where prebiotics come into play. What is considered a prebiotic? First on foremost, to understand prebiotic, we need to look at its official definition from international bodies and organization. Prebiotics are not just simply food for the gut microbiota. According to the\u00a0International Scientific Association for Probiotics and Prebiotics (ISAPP), a non-profit organization promoting the science of prebiotic and probiotic, a\u00a0prebiotic\u00a0is defined as: a substrate that is selectively utilized by host microorganisms\u00a0conferring a health benefit\u00a0[11]. The host microorganism here may refer to 2 things: (1) your innate gut microbiota as discussed in the section above, and (2) external supplementation in the form of probiotics. Other than being simply \u2018food\u2019 for these microorganisms, it also must confer \u2018health benefits\u2019 for a certain product to be classified as a prebiotic. By doing so, prebiotics\u00a0encourage the healthy balance\u00a0of your unique set of resident gut microbiota, creating an environment where the beneficial bacteria (such as\u00a0Lactobacillus\u00a0and\u00a0Bifidobacterium) flourish and\u00a0crowd out unwanted and harmful bacteria. The ISAPP has also noted that prebiotics are not the only substance that can affect the microbiota [11]. To qualify as a prebiotic, it must not only simply affect the microbiota, but it should also have selective effects on beneficial species like\u00a0Bifidobacterium. A prebiotic also needs have adequate evidence to show health benefits for the host, in this case humans [11]. Prebiotic: How it enhances your innate gut microbiota Prebiotics serve as a form of fuel for the gut microbiota. They are usually not digested and absorbed by the body and reaches the colon largely unchanged. The healthy gut microbiota then ferments the prebiotics. These fermentation process induces the proliferation of healthy gut bacterial species such as\u00a0Lactobacillus\u00a0and\u00a0Bifidobacterium\u00a0[12]. The fermentation process also produces metabolites such as\u00a0short-chain fatty acids (SCFAs). These SCFAs and other metabolites are involved in several biological process that confer health benefits to the host, such as glucose and lipid metabolism, immune function and regulating satiety [13]. By taking sufficient prebiotics, we would be able to maintain the level of our innate and beneficial gut bacteria (which is supposedly the most optimum set given to us by nature). Prebiotic: How it enhances probiotic supplements There are also benefits for those that are taking external probiotics supplements. Other than enhancing and supporting the growth of your healthy gut microbiota, prebiotics can also aid in maximizing the effects of your probiotic supplements. According to ISAPP, probiotics are defined as: live microorganisms that, when\u00a0administered in adequate amounts, confer a health benefit on the host [14]. The similar concept of conferring a health benefit applies. By taking prebiotics together with your probiotics, you may help to\u00a0improve the viability and survival chances\u00a0of the probiotics that"}